In July 2019, the Illinois Department of Public Health and the Wisconsin Department of Health Services launched a coordinated epidemiologic investigation after receiving reviews of a number of instances of lung injury in beforehand healthy individuals who reported electronic cigarette (e-cigarette) use, or vaping (1). This report describes features of e-cigarette product use by patients in Illinois and Wisconsin. While this investigation is ongoing, CDC recommends that persons consider refraining from utilizing e-cigarette, or vaping, merchandise, particularly these containing THC.

All five Cali Plug cartridges tested contained THC and MCT, however not vitamin E acetate. Bronchoalveolar lavage (BAL) fluid samples from five EVALI patients have been analyzed at CDC for energetic compounds and toxicants. Among the 20 examined cartridges seized throughout September 2019, all contained THC, vitamin E acetate, liquidmischen and MCT. Among merchandise seized during the 2018 raid, all five bulk liquid samples examined adverse for vitamin E acetate and liquidsezigaretten MCT; two examined optimistic for THC (Figure).

Among the seized merchandise examined by MDH, vapebasen none seized in 2018 contained vitamin E acetate, although all examined THC-containing merchandise seized in 2019 tested constructive for vitamin E acetate.

However, urinary THC screens were obtained for 32 patients who reported utilizing THC-containing merchandise, vapezubehor 29 (91%) of which had been positive for THC; two patients who didn't report utilizing THC-containing e-cigarette products, out of 4 examined, also had optimistic urinary THC screens; one of those patients reported smoking combustible marijuana.

Urinary toxicology screens had been optimistic for substances other than THC (and for other substances that couldn't be defined by the medical treatment these patients had acquired) in six of 31 patients, including two patients who examined constructive for benzodiazepines and opioids, one for benzodiazepines alone, one for opioids alone, one for amphetamines, and one for unspecified narcotics. These Minnesota findings highlight considerations about e-cigarette, or vaping, products that contain THC acquired from informal sources.

Because native provide chains and coverage environments range, dampfensale CDC continues to recommend not utilizing e-cigarette, vapebasen or vaping, products that contain THC or any e-cigarette, or vaping, products obtained from informal sources. Among the 86 interviewed patients, 75 (87%) reported using e-cigarette products containing THC, the principal psychoactive part of cannabis, throughout the 3 months preceding sickness; 61 (71%) reported utilizing nicotine-containing products; 50 (58%) reported utilizing both THC- and nicotine-containing merchandise.